Expert Video - What is AML with myelodysplasia-related changes (AML-MRC)?

Expert Dr. David Steensma explains in this video that acute myeloid leukemia with myelodysplasia-related changes is a specific type of AML. It is also called AML-MRC. In this type, the bone marrow not only has an unusually high number of the immature stem cells called blasts, but many other abnormal cells. These abnormalities are caused by a previous condition called myelodysplastic syndrome or by genetic changes. The outlook for AML-MRC is not as good as for other types of AML, but depends on what genetic abnormalities are present.

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Animation - Understanding AML-MRC and tAML

Slide Show - Understanding AML-MRC and tAML

Expert Videos

1. What is AML with myelodysplasia-related changes (AML-MRC)?

2. What is treatment-related AML (or tAML)?

3. What is secondary AML?

4. What are the symptoms of AML-MRC or tAML?

5. What are the risk factors for AML-MRC or tAML?

6. What is multilineage dysplasia?

7. What is the outlook for AML-MRC, tAML, and secondary AML?

Patient Videos

8. Mike's story: How did you find out you had AML?

9. Mike's story: What advice do you have for other patients on their journey with AML?

Other Modules:

Understanding AML

Understanding Erythropoiesis

Diagnosing AML, AML-MRC, and tAML

Treating AML

Treatment Failure and Relapse in AML

Maintenance and Continuous Treatment in AML

This educational activity has been developed by the Myelodysplastic Syndromes Foundation, Inc. and Mechanisms in Medicine Inc.

This activity is supported by educational grants from AbbVie, Acceleron, Bristol-Myers Squibb, Celgene Corporation, Daiichi Sankyo, Jazz Pharmaceuticals and Takeda Oncology.

This website is part of the Animated Patient™ series developed by Mechanisms in Medicine Inc., to provide highly visual formats of learning for patients to improve their understanding, make informed decisions, and partner with their healthcare professionals for optimal outcomes.